Robust bioinformatics to accelerate your discoveries
The large volume of data generated by high-throughput DNA sequencing requires rigorous bioinformatics workflows and advanced statistical analyses.
More than simply running pipelines, BiomeHub serves as your central bioinformatics and data analysis hub. You provide your raw sequencing data (FASTQ files) and experimental information (metadata), and our multidisciplinary team of specialists takes care of data processing, quality control, and statistical analysis—ensuring the traceability, reproducibility, and scientific reliability of your results.
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Validated pipelines for microbiome sequencing data
Our analyses rely on well-established tools and methodologies widely used by the microbiome research community, delivering reproducible results aligned with best practices in bioinformatics.
Amplicon Analysis (16S and ITS)
Characterization of microbial diversity using QIIME 2, with denoising through DADA2 and inference of amplicon sequence variants (ASVs), followed by taxonomic classification using publicly available reference databases.
Shotgun Metagenomics
Comprehensive characterization of the microbiome and its functional potential using the bioBakery pipeline, with high-resolution taxonomic profiling and functional annotation.
Analytical deliverables and statistical scope
We tailor the statistical analysis to your experimental design, including biological group comparisons, categorical variables, and longitudinal studies. All analyses include:
Alpha Diversity
Measures of within-sample microbial complexity, including richness, Shannon, Simpson, and Inverse Simpson indices.
Beta Diversity
Visualization of between-sample dissimilarity through PCoA and NMDS, using multiple distance metrics, including Bray-Curtis, Euclidean, Jaccard, UniFrac, and weighted UniFrac.
Taxonomic Profiles
Detailed taxonomic classification tables across multiple taxonomic levels.
Differential Abundance
Identification of differentially abundant microbial features using advanced statistical packages, including DESeq2, MaAsLin2, linDA, corncob, and limma-voom.
Visualizations
High-quality figures and tables designed to facilitate result interpretation and support scientific publications.
Alpha diversity
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Customized Bioinformatics Solutions
Does your project require approaches beyond standard methodological pipelines, or are you still evaluating the best analytical strategy for your data?
Share your study's biological questions and research objectives with us. Our team of specialists will design a custom bioinformatics workflow tailored to the specific requirements of your experimental design.
Go beyond static spreadsheets with EncodeReports
We believe in making scientific data more accessible and actionable. Your analysis is not delivered as static tables alone, it is made available through EncodeReports, our in-house data intelligence platform.
Publication-ready figures: Generate interactive plots, including PCoA, barplots, and heatmaps, and export them at high resolution, ready for use in your manuscript.
Integrated statistics: Explore and compare your data dynamically based on your metadata.
Collaboration and transparency: Easily and securely share results with co-authors and research collaborators.
Traceability and quality at every step
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Scientific alignment
Our team aligns the analytical approach with your project's biological questions and helps organize your clinical or experimental metadata.
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Secure Upload
Your FASTQ files, generated in your laboratory or by a third-party sequencing provider, are securely transferred to our servers.
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Processing and Quality Control
Bioinformatics pipelines are executed with full traceability, supporting the methodological reproducibility expected by scientific journals.
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Access to Results
Taxonomic profiles and statistical analyses are made available directly through EncodeReports for interactive exploration.
Elevate the impact of your research with high-quality analyses
Turn the challenge of data analysis into scientific clarity. Rely on our multidisciplinary team to unlock the full potential of your sequencing data, accelerate your research, and move your findings toward publication.
Note: All genomic data and clinical metadata are processed and stored under strict security and confidentiality protocols, following established best practices for data protection and research data management.
Frequent Asked Questions
